mrtf a inhibitor ccg 203971 (MedChemExpress)
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mrtf a inhibitor ccg 203971
Mrtf A Inhibitor Ccg 203971, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mrtf+a+inhibitor+ccg+203971/CCG-203971/bio_rxiv__64898__2026__03__03__709397-249-13-16
Average 94 stars, based on 3 article reviews
Mrtf A Inhibitor Ccg 203971, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mrtf+a+inhibitor+ccg+203971/CCG-203971/bio_rxiv__64898__2026__03__03__709397-249-13-16
Average 94 stars, based on 3 article reviews
mrtf a inhibitor ccg 203971 - by Bioz Stars,
2026-09
94/100 stars
Images
1) Product Images from "Myofibroblast lineage mapping and inhibiting subretinal fibrosis by targeting SMAD3 and MRTF pathways via microRNA-24 functional study"
Article Title: Myofibroblast lineage mapping and inhibiting subretinal fibrosis by targeting SMAD3 and MRTF pathways via microRNA-24 functional study
Journal: bioRxiv
doi: 10.64898/2026.03.03.709397
Figure Legend Snippet: a Representative immunostaining images showing repressed expression of Fibronectin and F-CHP staining by SMAD3 inhibitor (SIS3) at 10 μM or MRTF-A inhibitor (CCG-203971) at 20 μM, individually or in combination, in TGF-β2-treated ARPE-19 cells. B Quantification of ( a ). n=3. c Experimental timeline for evaluation of dual inhibition of SMAD3 and MRTF activity in the laser-induced subretinal fibrosis model. Representative three-dimensional reconstructions images showing RPE/choroid flatmount staining for F-CHP (green), Fibronectin (red), and α-SMA (magenta) are shown, with individual channels displayed below. d Quantification of ( c ). n = 6 mice per group, with 3 laser spots per eye. Eyes with hemorrhage after laser photocoagulation were excluded from analysis. *p < 0.05; * *p < 0.01; ***p < 0.001; ****p < 0.0001; ns, not significant.
Techniques Used: Immunostaining, Expressing, Staining, Inhibition, Activity Assay
Related Articles
Immunostaining:Article Title: Myofibroblast lineage mapping and inhibiting subretinal fibrosis by targeting SMAD3 and MRTF pathways via microRNA-24 functional study Article Snippet: In the first model, C57BL/6J mice were subjected to laser injury at 12 weeks of age.In the first model, C57BL/6J mice were subjected to laser injury at 12 weeks of age.. Beginning 7 days after laser photocoagulation, mice received daily intraperitoneal injections of the Expressing:Article Title: Myofibroblast lineage mapping and inhibiting subretinal fibrosis by targeting SMAD3 and MRTF pathways via microRNA-24 functional study Article Snippet: In the first model, C57BL/6J mice were subjected to laser injury at 12 weeks of age.In the first model, C57BL/6J mice were subjected to laser injury at 12 weeks of age.. Beginning 7 days after laser photocoagulation, mice received daily intraperitoneal injections of the Staining:Article Title: Myofibroblast lineage mapping and inhibiting subretinal fibrosis by targeting SMAD3 and MRTF pathways via microRNA-24 functional study Article Snippet: In the first model, C57BL/6J mice were subjected to laser injury at 12 weeks of age.In the first model, C57BL/6J mice were subjected to laser injury at 12 weeks of age.. Beginning 7 days after laser photocoagulation, mice received daily intraperitoneal injections of the Inhibition:Article Title: Myofibroblast lineage mapping and inhibiting subretinal fibrosis by targeting SMAD3 and MRTF pathways via microRNA-24 functional study Article Snippet: In the first model, C57BL/6J mice were subjected to laser injury at 12 weeks of age.In the first model, C57BL/6J mice were subjected to laser injury at 12 weeks of age.. Beginning 7 days after laser photocoagulation, mice received daily intraperitoneal injections of the Activity Assay:Article Title: Myofibroblast lineage mapping and inhibiting subretinal fibrosis by targeting SMAD3 and MRTF pathways via microRNA-24 functional study Article Snippet: In the first model, C57BL/6J mice were subjected to laser injury at 12 weeks of age.In the first model, C57BL/6J mice were subjected to laser injury at 12 weeks of age.. Beginning 7 days after laser photocoagulation, mice received daily intraperitoneal injections of the |